A challenge in developing microfluidic devices for fully portable and automated field analyses is the ability to integrate and store reagents in a stable form while maintaining a low cost for the system. Paper-based field-deployable devices are currently the most extensively explored platforms for field use; however, centrifugal devices offer a means for heightened device automation and portability. The basis for many field devices is chemical sensing via colorimetric reactions. The current project used various proof-of-principle colorimetric assays for multiple applications, including the analysis of total protein, serum albumin, cocaine, 2,4,6-trinitrotoluene (TNT), and iron content. Localized reagent integration facilitated by paper punches allowed for both reagent stability prior to reaction for storage, color stability post-reaction for image analysis, and was compatible for multi-step analyses. Qualitative and quantitative results were achieved with the broad range of sample applications trialed here, while still maintaining the ability for downstream processing. (Publisher abstract modified)
Downloads
Similar Publications
- American Indian and Alaska Native Persons in the Federal Criminal Justice System, 2023
- Introducing "DoPP": A Graphical User-Friendly Application for the Rapid Species Identification of Psychoactive Plant Materials and Quantification of Psychoactive Small Molecules Using DART-MS Data
- Development of a THC Breath Analyzer using Chitosan Film with Colorimetric Dye